Genetically designing a more potent anti-pancreatic cancer agent by simultaneously cotargeting human IL-13 and EGF receptors in a mouse xenograft model

OBJECTIVE: Investigators are currently interested in the EGFR and IL-13R as potential targets in the development of new biologicals for pancreatic cancer. Attempts to develop successful agents have met with difficulty. Our novel approach was to simultaneously target these receptors with EGF and IL-1...

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Bibliographic Details
Main Authors: Vallera, Daniel A, Stish, Brad J., Shu, Yanqun, Chen, Hua, Saluja, Ashok, Buchsbaum, Donald J., Vickers, Selwyn M.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756191/
https://ncbi.nlm.nih.gov/pubmed/18222985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.137802
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