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A novel “reduced immunogenicity” bispecific targeted toxin simultaneously recognizing human EGF and IL-4 receptors in a mouse model of metastatic breast carcinoma
PURPOSE: To develop a targeted biological drug that when injected systemically can penetrate to metastatic breast cancer tumors, one needs a drug of high potency and “reduced immunogenicity”. Thus, we bioengineered a novel bispecific ligand directed toxin (BLT) targeted by dual high affinity cytokin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756320/ https://ncbi.nlm.nih.gov/pubmed/19789305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0696 |
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