Molecular Determinants of the Coupling between STIM1 and Orai Channels: DIFFERENTIAL ACTIVATION OF Orai1–3 CHANNELS BY A STIM1 COILED-COIL MUTANT

STIM1 and Orai1 have been reported to interact upon store depletion culminating in Ca(2+) release-activated Ca(2+) current activation. Recently, the essential region has been identified within the STIM1 C terminus that includes the second coiled-coil domain C-terminally extended by ∼50 amino acids a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Frischauf, Irene, Muik, Martin, Derler, Isabella, Bergsmann, Judith, Fahrner, Marc, Schindl, Rainer, Groschner, Klaus, Romanin, Christoph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mechanisms of Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755892/
https://ncbi.nlm.nih.gov/pubmed/19506081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018408
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