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LFA-1 and CD2 Synergize for the Erk1/2 Activation in the Natural Killer (NK) Cell Immunological Synapse

Natural killer (NK) cell recognition and formation of a conjugate with target cells, followed by intracellular signal pathway activation and degradation of cytolytic granules, are essential for NK cell cytotoxicity. In this study, NK92 cells were used to investigate synapse formation and subsequent...

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Main Authors: Zheng, Xiaodong, Wang, Yanyan, Wei, Haiming, Sun, Rui, Tian, Zhigang
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755852/
https://ncbi.nlm.nih.gov/pubmed/19502238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807053200
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