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LFA-1 and CD2 Synergize for the Erk1/2 Activation in the Natural Killer (NK) Cell Immunological Synapse

Natural killer (NK) cell recognition and formation of a conjugate with target cells, followed by intracellular signal pathway activation and degradation of cytolytic granules, are essential for NK cell cytotoxicity. In this study, NK92 cells were used to investigate synapse formation and subsequent...

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Hlavní autoři: Zheng, Xiaodong, Wang, Yanyan, Wei, Haiming, Sun, Rui, Tian, Zhigang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755852/
https://ncbi.nlm.nih.gov/pubmed/19502238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807053200
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