Chargement en cours...
F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse
Integrin-dependent interactions between T cells and antigen-presenting cells are vital for proper T cell activation, effector function, and memory. Regulation of integrin function occurs via conformational change, which modulates ligand affinity, and receptor clustering, which modulates valency. Her...
Enregistré dans:
| Publié dans: | J Cell Biol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332248/ https://ncbi.nlm.nih.gov/pubmed/25666810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406121 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|