Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse

Full T cell activation requires coordination of signals from multiple receptor–ligand pairs that interact in parallel at a specialized cell–cell contact site termed the immunological synapse (IS). Signaling at the IS is intimately associated with actin dynamics; T cell receptor (TCR) engagement indu...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Jankowska, Katarzyna I., Williamson, Edward K., Roy, Nathan H., Blumenthal, Daniel, Chandra, Vidhi, Baumgart, Tobias, Burkhardt, Janis K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778112/
https://ncbi.nlm.nih.gov/pubmed/29403502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00025
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