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LFA-1 and CD2 Synergize for the Erk1/2 Activation in the Natural Killer (NK) Cell Immunological Synapse

Natural killer (NK) cell recognition and formation of a conjugate with target cells, followed by intracellular signal pathway activation and degradation of cytolytic granules, are essential for NK cell cytotoxicity. In this study, NK92 cells were used to investigate synapse formation and subsequent...

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Detalhes bibliográficos
Main Authors: Zheng, Xiaodong, Wang, Yanyan, Wei, Haiming, Sun, Rui, Tian, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755852/
https://ncbi.nlm.nih.gov/pubmed/19502238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807053200
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