CD226 Protein Is Involved in Immune Synapse Formation and Triggers Natural Killer (NK) Cell Activation via Its First Extracellular Domain

CD226, an activating receptor that interacts with the ligands CD155 and CD112, activates natural killer (NK) cells via its immunoreceptor tyrosine-based activatory motif (ITAM). There are two extracellular domains of CD226; however, the comparative functional relevance of these domains remains unkno...

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Main Authors: Hou, Shengke, Ge, Kuikui, Zheng, Xiaodong, Wei, Haiming, Sun, Rui, Tian, Zhigang
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945358/
https://ncbi.nlm.nih.gov/pubmed/24451371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498253
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