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Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro
Termination of RNA polymerase (pol) II transcription in vivo requires the 5′-RNA exonuclease Rat1. It was proposed that Rat1 degrades RNA from the 5′-end that is created by transcript cleavage, catches up with elongating pol II, and acts like a Torpedo that removes pol II from DNA. Here we test the...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755851/ https://ncbi.nlm.nih.gov/pubmed/19535338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013847 |
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