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RNA Polymerase II C-terminal Heptarepeat Domain Ser-7 Phosphorylation Is Established in a Mediator-dependent Fashion

The largest subunit of RNA polymerase II (RNAPII) C-terminal heptarepeat domain (CTD) is subject to phosphorylation during initiation and elongation of transcription by RNA polymerase II. Here we study the molecular mechanisms leading to phosphorylation of Ser-7 in the human enzyme. Ser-7 becomes ph...

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Detalhes bibliográficos
Main Authors: Boeing, Stefan, Rigault, Caroline, Heidemann, Martin, Eick, Dirk, Meisterernst, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804165/
https://ncbi.nlm.nih.gov/pubmed/19901026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046565
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