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C-terminal Repeat Domain Kinase I Phosphorylates Ser2 and Ser5 of RNA Polymerase II C-terminal Domain Repeats

The C-terminal repeat domain (CTD) of the largest subunit of RNA polymerase II is composed of tandem heptad repeats with consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. In yeast, this heptad sequence is repeated about 26 times, and it becomes hyperphosphorylated during transcription predomina...

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Hlavní autoři: Jones, Janice C., Phatnani, Hemali P., Haystead, Timothy A., MacDonald, Justin A., Alam, S. Munir, Greenleaf, Arno L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680323/
https://ncbi.nlm.nih.gov/pubmed/15047695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M402218200
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