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Unraveling the mechanistic features of RNA polymerase II termination by the 5′-3′ exoribonuclease Rat1

Within a complex with Rai1, the 5′-3′ exoribonuclease Rat1 promotes termination of RNA polymerase II (RNAPII) on protein-coding genes, but its underlying molecular mechanism is still poorly understood. Using in vitro transcription termination assays, we have found that RNAPII is prone to more effect...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Park, Jieun, Kang, Myungjin, Kim, Minkyu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357727/
https://ncbi.nlm.nih.gov/pubmed/25722373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv133
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