Ładuje się......
Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation
Loss-of-function mutations in the parkin gene (PARK2) and PINK1 gene (PARK6) are associated with autosomal recessive parkinsonism. PINK1 deficiency was recently linked to mitochondrial pathology in human cells and Drosophila melanogaster, which can be rescued by parkin, suggesting that both genes pl...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2009
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755701/ https://ncbi.nlm.nih.gov/pubmed/19546216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035774 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|