The Caenorhabditis elegans Aβ(1–42) Model of Alzheimer Disease Predominantly Expresses Aβ(3–42)

Transgenic expression of human amyloid β (Aβ) peptide in body wall muscle cells of Caenorhabditis elegans has been used to better understand aspects of Alzheimer disease (AD). In human aging and AD, Aβ undergoes post-translational changes including covalent modifications, truncations, and oligomeriz...

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Detalhes bibliográficos
Main Authors: McColl, Gawain, Roberts, Blaine R., Gunn, Adam P., Perez, Keyla A., Tew, Deborah J., Masters, Colin L., Barnham, Kevin J., Cherny, Robert A., Bush, Ashley I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Synthesis, Post-Translational Modification, and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755678/
https://ncbi.nlm.nih.gov/pubmed/19574211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.028514
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