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Fitness cost of extended lifespan in Caenorhabditis elegans.
An insulin/IGF-I-like signalling pathway determines the rate of aging of the adult nematode, Caenorhabditis elegans. Mutations in genes encoding this pathway can result in a doubling of lifespan. While such mutations may appear to have little effect on development or fertility, evolutionary theory p...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440519/ https://ncbi.nlm.nih.gov/pubmed/15590605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2004.2897 |
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