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Fitness cost of extended lifespan in Caenorhabditis elegans.

An insulin/IGF-I-like signalling pathway determines the rate of aging of the adult nematode, Caenorhabditis elegans. Mutations in genes encoding this pathway can result in a doubling of lifespan. While such mutations may appear to have little effect on development or fertility, evolutionary theory p...

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Main Authors: Jenkins, Nicole L., McColl, Gawain, Lithgow, Gordon J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440519/
https://ncbi.nlm.nih.gov/pubmed/15590605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2004.2897
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