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Pharmacogenetic Analysis of Lithium-induced Delayed Aging in Caenorhabditis elegans

Lithium (Li(+)) has been used to treat mood affect disorders, including bipolar, for decades. This drug is neuroprotective and has several identified molecular targets. However, it has a narrow therapeutic range and the one or more underlying mechanisms of its therapeutic action are not understood....

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Detalhes bibliográficos
Main Authors: McColl, Gawain, Killilea, David W., Hubbard, Alan E., Vantipalli, Maithili C., Melov, Simon, Lithgow, Gordon J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739662/
https://ncbi.nlm.nih.gov/pubmed/17959600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705028200
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