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Direct Interdomain Interactions Can Mediate Allosterism in the Thyroid Receptor
The thyroid (TR) and retinoid X receptors (RXR) belong to the nuclear receptor (NR) superfamily of ligand-mediated transcription factors. At the molecular level, TR activity is specifically modulated by interactions with the ligand 3,3′,5 triiodo-l-thyronine (T3), RXR, DNA, and co-activators such as...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755658/ https://ncbi.nlm.nih.gov/pubmed/19561066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026682 |
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