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A Bayesian hierarchical nonlinear model for assessing the association between genetic variation and drug cytotoxicity

Non-tumor cell based model systems have recently gained interest in pharmacogenetic research as a hypothesis generating tool. The hypotheses generated from these model systems can be followed up in functional studies, or tested in individuals taking the same investigational agents. The current cellu...

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Autors principals: Fridley, Brooke L., Jenkins, Greg, Schaid, Daniel J., Wang, Liewei
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755562/
https://ncbi.nlm.nih.gov/pubmed/19572260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3649
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