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Identifying the Genetic Variation of Gene Expression Using Gene Sets: Application of Novel Gene Set eQTL Approach to PharmGKB and KEGG

Genetic variation underlying the regulation of mRNA gene expression in humans may provide key insights into the molecular mechanisms of human traits and complex diseases. Current statistical methods to map genetic variation associated with mRNA gene expression have typically applied standard linkage...

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Detalhes bibliográficos
Main Authors: Abo, Ryan, Jenkins, Gregory D., Wang, Liewei, Fridley, Brooke L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419168/
https://ncbi.nlm.nih.gov/pubmed/22905253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043301
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