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Localizing Putative Markers in Genetic Association Studies by Incorporating Linkage Disequilibrium into Bayesian Hierarchical Models

OBJECTIVE: Numerous methods have been proposed to model the association between multiple single nucleotide polymorphisms (SNPs) and a phenotype. Often these methods do not explicitly model the information regarding the linkage disequilibrium (LD) between SNPs. Furthermore, many methods shrink the SN...

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Bibliografiske detaljer
Main Authors: Fridley, Brooke L., Jenkins, Gregory D.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918651/
https://ncbi.nlm.nih.gov/pubmed/20551675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000313852
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