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Localizing Putative Markers in Genetic Association Studies by Incorporating Linkage Disequilibrium into Bayesian Hierarchical Models
OBJECTIVE: Numerous methods have been proposed to model the association between multiple single nucleotide polymorphisms (SNPs) and a phenotype. Often these methods do not explicitly model the information regarding the linkage disequilibrium (LD) between SNPs. Furthermore, many methods shrink the SN...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
S. Karger AG
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918651/ https://ncbi.nlm.nih.gov/pubmed/20551675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000313852 |
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