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Using Object Oriented Bayesian Networks to Model Linkage, Linkage Disequilibrium and Mutations between STR Markers

In a number of applications there is a need to determine the most likely pedigree for a group of persons based on genetic markers. Adequate models are needed to reach this goal. The markers used to perform the statistical calculations can be linked and there may also be linkage disequilibrium (LD) i...

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Bibliographic Details
Main Authors: Kling, Daniel, Egeland, Thore, Mostad, Petter
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439468/
https://ncbi.nlm.nih.gov/pubmed/22984448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043873
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