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Using Object Oriented Bayesian Networks to Model Linkage, Linkage Disequilibrium and Mutations between STR Markers

In a number of applications there is a need to determine the most likely pedigree for a group of persons based on genetic markers. Adequate models are needed to reach this goal. The markers used to perform the statistical calculations can be linked and there may also be linkage disequilibrium (LD) i...

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Detalhes bibliográficos
Main Authors: Kling, Daniel, Egeland, Thore, Mostad, Petter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439468/
https://ncbi.nlm.nih.gov/pubmed/22984448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043873
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