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Functional Rescue of β(1)-Adrenoceptor Dimerization and Trafficking by Pharmacological Chaperones
Site-directed mutagenesis guided by evolutionary trace analysis revealed that substitution of V179 and W183 within a cluster of evolutionarily important residues on the surface of the fourth transmembrane domain of the β(1)-adrenergic receptor (β(1)AR) significantly reduced the propensity of the rec...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755524/ https://ncbi.nlm.nih.gov/pubmed/19515093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2009.00932.x |
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