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Exploring the mechanism of βamyloid toxicity attenuation by multivalent sialic acid polymers through the use of mathematical models
β-Amyloid peptide (Aβ), the primary protein component in senile plaques associated with Alzheimer’s disease (AD), has been implicated in neurotoxicity associated with AD. Previous studies have shown that the Aβ-neuronal membrane interaction plays a role in the mechanism of Aβ toxicity. More specific...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755187/ https://ncbi.nlm.nih.gov/pubmed/19217912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.02.003 |
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