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Structurally distinct toxicity inhibitors bind at common loci on β-amyloid fibril
The accumulation of aggregated β-Amyloid (Aβ) in the brain is a hallmark of Alzheimer's disease and is thought to play a role in the neurotoxicity associated with the disease. The mechanism by which Aβ aggregates induce toxicity is uncertain. Nonetheless, several small molecules have been found...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009397/ https://ncbi.nlm.nih.gov/pubmed/20882638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.509 |
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