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Formation of Toxic Amyloid Fibrils by Amyloid β-Protein on Ganglioside Clusters
It is widely accepted that the conversion of the soluble, nontoxic amyloid β-protein (Aβ) monomer to aggregated toxic Aβ rich in β-sheet structures is central to the development of Alzheimer's disease. However, the mechanism of the abnormal aggregation of Aβ in vivo is not well understood. Accu...
Kaydedildi:
| Yazar: | |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
SAGE-Hindawi Access to Research
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034960/ https://ncbi.nlm.nih.gov/pubmed/21318142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/956104 |
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