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The Formation of Fibrils by Intertwining of Filaments: Model and Application to Amyloid Aβ Protein

We outline a model that describes the interaction of rods that form intertwined bundles. In this simple model, we compare the elastic energy penalty that arises due to the deformation of the rods to the gain in binding energy upon intertwining. We find that, for proper values of the bending Young�...

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Bibliografiske detaljer
Main Authors: van Gestel, Jeroen, de Leeuw, Simon W.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783885/
https://ncbi.nlm.nih.gov/pubmed/17114229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097535
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