Llwytho...
Temperature-Induced Dissociation of Aβ Monomers from Amyloid Fibril
Using all-atom molecular dynamics, we study the temperature-induced dissociation of Aβ monomers from the fibril protofilament. To accelerate conformational sampling, simulations are performed at elevated temperatures and peptide concentrations. By computing free energy disconnectivity graphs we mapp...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The Biophysical Society
2008
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483770/ https://ncbi.nlm.nih.gov/pubmed/18502791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131698 |
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