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Exploring the mechanism of βamyloid toxicity attenuation by multivalent sialic acid polymers through the use of mathematical models

β-Amyloid peptide (Aβ), the primary protein component in senile plaques associated with Alzheimer’s disease (AD), has been implicated in neurotoxicity associated with AD. Previous studies have shown that the Aβ-neuronal membrane interaction plays a role in the mechanism of Aβ toxicity. More specific...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cowan, Christopher B., Patel, Dhara A., Good, Theresa A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755187/
https://ncbi.nlm.nih.gov/pubmed/19217912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.02.003
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