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Attenuation of β-amyloid induced toxicity by sialic acid-conjugated dendrimers: role of sialic acid attachment
β-amyloid (Aβ) is the primary protein component of senile plaques in Alzheimer’s disease and is believed to be associated with neurotoxicity in the disease. We and others have shown that Aβ binds with relatively high affinity to clustered sialic acid residues on cell surfaces and that removal of cel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2031224/ https://ncbi.nlm.nih.gov/pubmed/17604005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.05.055 |
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