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A Foldamer-Dendrimer Conjugate Neutralizes Synaptotoxic β-Amyloid Oligomers
BACKGROUND AND AIMS: Unnatural self-organizing biomimetic polymers (foldamers) emerged as promising materials for biomolecule recognition and inhibition. Our goal was to construct multivalent foldamer-dendrimer conjugates which wrap the synaptotoxic β-amyloid (Aβ) oligomers with high affinity throug...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408453/ https://ncbi.nlm.nih.gov/pubmed/22859942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039485 |
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