Abeta(1-42) Enhances Neuronal Excitability in the CA1 via NR2B Subunit-Containing NMDA Receptors

Neuronal hyperexcitability is a phenomenon associated with early Alzheimer's disease. The underlying mechanism is considered to involve excessive activation of glutamate receptors; however, the exact molecular pathway remains to be determined. Extracellular recording from the CA1 of hippocampal...

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Bibliographic Details
Main Authors: Varga, Edina, Juhász, Gábor, Bozsó, Zsolt, Penke, Botond, Fülöp, Lívia, Szegedi, Viktor
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168240/
https://ncbi.nlm.nih.gov/pubmed/25276438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/584314
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