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Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice
Hsp27 belongs to the small heat shock protein family, which are ATP-independent chaperones. The most important function of Hsp27 is based on its ability to bind non-native proteins and inhibit the aggregation of incorrectly folded proteins maintaining them in a refolding-competent state. Additionall...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer Netherlands
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789881/ https://ncbi.nlm.nih.gov/pubmed/23605646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-013-0428-9 |
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