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Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice

AIMS: ApoB-100 is the major protein component of cholesterol- and triglyceride-rich LDL and VLDL lipoproteins in the serum. Previously, we generated and partially described transgenic mice overexpressing the human ApoB-100 protein. Here, we further characterize this transgenic strain in order to rev...

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Detalhes bibliográficos
Main Authors: Lénárt, Nikolett, Szegedi, Viktor, Juhász, Gábor, Kasztner, Aniko, Horváth, János, Bereczki, Erika, Tóth, Melinda E., Penke, Botond, Sántha, Miklós
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454377/
https://ncbi.nlm.nih.gov/pubmed/23029362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046007
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