Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice

Hsp27 belongs to the small heat shock protein family, which are ATP-independent chaperones. The most important function of Hsp27 is based on its ability to bind non-native proteins and inhibit the aggregation of incorrectly folded proteins maintaining them in a refolding-competent state. Additionall...

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Hlavní autoři: Tóth, Melinda Erzsébet, Szegedi, Viktor, Varga, Edina, Juhász, Gábor, Horváth, János, Borbély, Emőke, Csibrány, Balázs, Alföldi, Róbert, Lénárt, Nikolett, Penke, Botond, Sántha, Miklós
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2013
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789881/
https://ncbi.nlm.nih.gov/pubmed/23605646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-013-0428-9
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