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Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers

Alzheimer’s disease is one of the most common chronic neurodegenerative disorders. Despite several in vivo and clinical studies, the cause of the disease is poorly understood. Currently, amyloid β (Aβ) peptide and its tendency to assemble into soluble oligomers are known as a main pathogenic event l...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Bartus, Éva, Olajos, Gábor, Schuster, Ildikó, Bozsó, Zsolt, Deli, Mária A., Veszelka, Szilvia, Walter, Fruzsina R., Datki, Zsolt, Szakonyi, Zsolt, Martinek, Tamás A., Fülöp, Livia
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222781/
https://ncbi.nlm.nih.gov/pubmed/30279351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102523
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