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Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers

Alzheimer’s disease is one of the most common chronic neurodegenerative disorders. Despite several in vivo and clinical studies, the cause of the disease is poorly understood. Currently, amyloid β (Aβ) peptide and its tendency to assemble into soluble oligomers are known as a main pathogenic event l...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Bartus, Éva, Olajos, Gábor, Schuster, Ildikó, Bozsó, Zsolt, Deli, Mária A., Veszelka, Szilvia, Walter, Fruzsina R., Datki, Zsolt, Szakonyi, Zsolt, Martinek, Tamás A., Fülöp, Livia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222781/
https://ncbi.nlm.nih.gov/pubmed/30279351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102523
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