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Methylation of 2’-Deoxyguanosine by a Free Radical Mechanism
The mechanistic aspects of the methylation of guanine in DNA initiated by methyl radicals that are derived from the metabolic oxidation of some chemical carcinogens remain poorly understood. In this work we investigated the kinetics and the formation of methylated guanine products by two methods: (i...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754879/ https://ncbi.nlm.nih.gov/pubmed/19719172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp903554n |
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