S-Adenosylmethionine in the Chemoprevention and Treatment of Hepatocellular Carcinoma in a Rat Model

BACKGROUND AND RATIONALE: Hepatocellular carcinoma (HCC) remains a common cancer worldwide that lacks effective chemoprevention or treatment. Chronic liver disease often leads to impaired hepatic S-adenosylmethionine (SAMe) biosynthesis and mice with SAMe deficiency develop HCC spontaneously. SAMe i...

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Bibliografski detalji
Glavni autori: Lu, Shelly C., Ramani, Komal, Ou, Xiaopeng, Lin, Mark, Yu, Victor, Ko, Kwangsuk, Park, Ryan, Bottiglieri, Teodoro, Tsukamoto, Hidekazu, Kanel, Gary, French, Samuel W., Mato, José M., Moats, Rex, Grant, Edward
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754739/
https://ncbi.nlm.nih.gov/pubmed/19444874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22990
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