S-Adenosylmethionine in the Chemoprevention and Treatment of Hepatocellular Carcinoma in a Rat Model

BACKGROUND AND RATIONALE: Hepatocellular carcinoma (HCC) remains a common cancer worldwide that lacks effective chemoprevention or treatment. Chronic liver disease often leads to impaired hepatic S-adenosylmethionine (SAMe) biosynthesis and mice with SAMe deficiency develop HCC spontaneously. SAMe i...

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Detalhes bibliográficos
Main Authors: Lu, Shelly C., Ramani, Komal, Ou, Xiaopeng, Lin, Mark, Yu, Victor, Ko, Kwangsuk, Park, Ryan, Bottiglieri, Teodoro, Tsukamoto, Hidekazu, Kanel, Gary, French, Samuel W., Mato, José M., Moats, Rex, Grant, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754739/
https://ncbi.nlm.nih.gov/pubmed/19444874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22990
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