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Hepatic Insulin Resistance Directly Promotes Formation of Cholesterol Gallstones
Despite the well-documented association between gallstones and the metabolic syndrome1,2, the mechanistic links between these two disorders remain unknown. Here we demonstrate that mice with isolated hepatic insulin resistance created by liver-specific disruption of the insulin receptor (LIRKO mice)...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2753607/ https://ncbi.nlm.nih.gov/pubmed/18587407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1785 |
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