Hepatic Insulin Resistance Directly Promotes Formation of Cholesterol Gallstones

Despite the well-documented association between gallstones and the metabolic syndrome1,2, the mechanistic links between these two disorders remain unknown. Here we demonstrate that mice with isolated hepatic insulin resistance created by liver-specific disruption of the insulin receptor (LIRKO mice)...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Biddinger, Sudha B., Haas, Joel T., Yu, Bian B., Bezy, Olivier, Jing, Enxuan, Zhang, Wenwei, Unterman, Terry G., Carey, Martin C., Kahn, C. Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753607/
https://ncbi.nlm.nih.gov/pubmed/18587407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1785
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky