Hepatic Insulin Resistance Directly Promotes Formation of Cholesterol Gallstones

Despite the well-documented association between gallstones and the metabolic syndrome1,2, the mechanistic links between these two disorders remain unknown. Here we demonstrate that mice with isolated hepatic insulin resistance created by liver-specific disruption of the insulin receptor (LIRKO mice)...

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Detaylı Bibliyografya
Asıl Yazarlar: Biddinger, Sudha B., Haas, Joel T., Yu, Bian B., Bezy, Olivier, Jing, Enxuan, Zhang, Wenwei, Unterman, Terry G., Carey, Martin C., Kahn, C. Ronald
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753607/
https://ncbi.nlm.nih.gov/pubmed/18587407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1785
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