Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System

To test a previously coined “charge balance hypothesis” of human hepatitis B virus (HBV) capsid stability, we established an in vitro disassembly and reassembly system using bacterially expressed HBV capsids. Capsid disassembly can be induced by micrococcal nuclease digestion of encapsidated RNA. HB...

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Bibliografiska uppgifter
Huvudupphovsmän: Newman, Margaret, Chua, Pong Kian, Tang, Fan-Mei, Su, Pei-Yi, Shih, Chiaho
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Structure and Assembly
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753136/
https://ncbi.nlm.nih.gov/pubmed/19656897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00749-09
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