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Coexistence of Two Distinct Secretion Mutations (P5T and I97L) in Hepatitis B Virus Core Produces a Wild-Type Pattern of Secretion

Unlike a Tokyo isolate of hepatitis B virus variants, we found a Shanghai isolate that secretes few virions with an immature genome despite its core I97L mutation. Core mutations P5T and I97L were found to be mutually compensatory in offsetting their respective distinct effects on virion secretion.

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chua, Pong Kian, Wen, Yu-Mei, Shih, Chiaho
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2003
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164791/
https://ncbi.nlm.nih.gov/pubmed/12805468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7673-7676.2003
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