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The Mechanism of an Immature Secretion Phenotype of a Highly Frequent Naturally Occurring Missense Mutation at Codon 97 of Human Hepatitis B Virus Core Antigen

A very frequent missense mutation at codon 97 of human hepatitis B virus (HBV) core antigen (HBcAg) has been found in chronic carriers worldwide. Functional characterization of this mutant revealed one intracellular and two extracellular phenotypes in contrast to wild-type HBV: (i) a 6- to 12-fold d...

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Библиографические подробности
Главные авторы: Yuan, Thomas Ta-Tung, Sahu, Gautam Kumar, Whitehead, William E., Greenberg, Richard, Shih, Chiaho
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC112633/
https://ncbi.nlm.nih.gov/pubmed/10364324
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