The Mechanism of an Immature Secretion Phenotype of a Highly Frequent Naturally Occurring Missense Mutation at Codon 97 of Human Hepatitis B Virus Core Antigen

A very frequent missense mutation at codon 97 of human hepatitis B virus (HBV) core antigen (HBcAg) has been found in chronic carriers worldwide. Functional characterization of this mutant revealed one intracellular and two extracellular phenotypes in contrast to wild-type HBV: (i) a 6- to 12-fold d...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Yuan, Thomas Ta-Tung, Sahu, Gautam Kumar, Whitehead, William E., Greenberg, Richard, Shih, Chiaho
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364324/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.7.5731-5740.1999
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