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Coexistence of Two Distinct Secretion Mutations (P5T and I97L) in Hepatitis B Virus Core Produces a Wild-Type Pattern of Secretion

Unlike a Tokyo isolate of hepatitis B virus variants, we found a Shanghai isolate that secretes few virions with an immature genome despite its core I97L mutation. Core mutations P5T and I97L were found to be mutually compensatory in offsetting their respective distinct effects on virion secretion.

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:J Virol
Príomhchruthaitheoirí: Chua, Pong Kian, Wen, Yu-Mei, Shih, Chiaho
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 2003
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7673-7676.2003
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