Coexistence of Two Distinct Secretion Mutations (P5T and I97L) in Hepatitis B Virus Core Produces a Wild-Type Pattern of Secretion

Unlike a Tokyo isolate of hepatitis B virus variants, we found a Shanghai isolate that secretes few virions with an immature genome despite its core I97L mutation. Core mutations P5T and I97L were found to be mutually compensatory in offsetting their respective distinct effects on virion secretion.

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Chua, Pong Kian, Wen, Yu-Mei, Shih, Chiaho
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7673-7676.2003
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!