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Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System

To test a previously coined “charge balance hypothesis” of human hepatitis B virus (HBV) capsid stability, we established an in vitro disassembly and reassembly system using bacterially expressed HBV capsids. Capsid disassembly can be induced by micrococcal nuclease digestion of encapsidated RNA. HB...

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Hlavní autoři: Newman, Margaret, Chua, Pong Kian, Tang, Fan-Mei, Su, Pei-Yi, Shih, Chiaho
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753136/
https://ncbi.nlm.nih.gov/pubmed/19656897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00749-09
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