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Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System

To test a previously coined “charge balance hypothesis” of human hepatitis B virus (HBV) capsid stability, we established an in vitro disassembly and reassembly system using bacterially expressed HBV capsids. Capsid disassembly can be induced by micrococcal nuclease digestion of encapsidated RNA. HB...

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Detalhes bibliográficos
Main Authors: Newman, Margaret, Chua, Pong Kian, Tang, Fan-Mei, Su, Pei-Yi, Shih, Chiaho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753136/
https://ncbi.nlm.nih.gov/pubmed/19656897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00749-09
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