Testing an Electrostatic Interaction Hypothesis of Hepatitis B Virus Capsid Stability by Using an In Vitro Capsid Disassembly/Reassembly System

To test a previously coined “charge balance hypothesis” of human hepatitis B virus (HBV) capsid stability, we established an in vitro disassembly and reassembly system using bacterially expressed HBV capsids. Capsid disassembly can be induced by micrococcal nuclease digestion of encapsidated RNA. HB...

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Bibliographic Details
Main Authors: Newman, Margaret, Chua, Pong Kian, Tang, Fan-Mei, Su, Pei-Yi, Shih, Chiaho
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753136/
https://ncbi.nlm.nih.gov/pubmed/19656897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00749-09
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