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Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly

The HIV-1 core consists of the viral genomic RNA and several viral proteins encased within a conical capsid. After cell entry, the core disassembles in a process termed uncoating. Although HIV-1 uncoating has been linked to reverse transcription of the viral genome in target cells, the mechanism by...

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Publicado en:J Virol
Autores principales: Rankovic, Sanela, Varadarajan, Janani, Ramalho, Ruben, Aiken, Christopher, Rousso, Itay
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446659/
https://ncbi.nlm.nih.gov/pubmed/28381579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00289-17
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